Sinonasal Tract Mucosal Melanoma
نویسندگان
چکیده
منابع مشابه
Sinonasal tract mucosal melanoma.
Mucosal melanoma is a neural-crest–derived neoplasm that originates in melanocytes and demonstrates melanocytic differentiation. Exposure to formalin and ultraviolet light are known etiologic factors; another possible factor is exposure to radiation. Approximately 15 to 20% of all skin melanomas develop on the head and neck, but less than 1% of all melanomas develop in ocular or mucosal sites, ...
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Sinonasal mucosal melanoma (SMM) is an aggressive and rare type of melanoma. Although the classic RAS-RAF-MEK pathway is thought to be the main pathway involved in melanoma pathogenesis, genetic alterations in the phosphatidylinositol 3-kinase-AKT pathway, including PTEN-regulated signaling, are also thought to contribute. So far, data regarding altered PTEN expression and epigenetic mechanism ...
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BACKGROUND The significance of definitive radiotherapy for sinonasal mucosal melanoma (SMM) is sill controvertial. This study was to evaluate the role of high-dose proton beam therapy (PBT) in patients with SMM. METHODS The cases of 20 patients with SMM localized to the primary site who were treated by PBT between 2006 and 2012 were retrospectively analyzed. The patterns of overall survival a...
متن کامل[Primary mucosal melanoma of the sinonasal tract: report of 18 patients and analysis of 1077 patients in the literature].
UNLABELLED The present study aimed at reporting on the characteristics, prognostic factors and treatment outcomes of 18 cases of nasosinusal mucosa melanoma, and do a literature review on the subject. METHODS between 1995 and 2005, 18 patients consecutively diagnosed with nasosinusal mucosa melanoma were managed in our institution. We reviewed the literature in PubMed and Scopus in order to f...
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Sinus mucosal malignant melanoma, is a rare type of melanoma with poor prognosis which is usually occurred in the adults. This is a rare case of a 33-year-old man presenting 2-week-long headache and nasal obstruction with the emphasis on the importance of Immunohistochemical staining to help the diagnosis.
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ژورنال
عنوان ژورنال: Ear, Nose & Throat Journal
سال: 2014
ISSN: 0145-5613,1942-7522
DOI: 10.1177/014556131409310-1108